Botox dose vs benefit
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Posted by: Jon Holder ®

11/28/2002, 22:22:13
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I have been getting Botox shots for AD/SD for ten years now.

Mostly from Dr. Brin but more recently from Dr. Blitzer. The

shots have always been Bilateral and very effective lasting

six months and giving me a completely normal voice for about

four months. The only problem was a loss of voice for three to

four weeks after the shot. So the last time Dr. Blitzer lowered

the dose from .3 to .25 to see if that would help. The result

was the same four weeks of recovery but the spasms are still

there! Guess I have proven to myself that dosage has little

relationship to recovery time but could have a big effect on

the benefit you get. I have only had about 20 shots total so

hopefully this is not a scar tissue issue. Do I go back after

only two months and try the old dose of .3? Botox has been so

consistent for me for so long that I guess I started taking it

for granted. This is very disturbing new ground for me.






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Re: Botox dose vs benefit
Re: Botox dose vs benefit -- Jon Holder Top of Thread Archive
Posted by: David Barton (NZ) ®

11/29/2002, 02:53:12
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Jon, sorry to hear that you've experienced this problem after having had a good run in the past.

When my doctors, several years ago, kept lowering the dose of bilateral injections to help with the breathiness or 'loss of voice' you describe, the result was that the benefit didn't last as long. At one point they repeated shots (dose was about 0.3 units) after only 6 weeks - I wouldn't recommend that generally as too frequent injections might raise the risk of developing immunity to the Botox.

My advice, initially, would be to go back to what has worked in the past for you - but if it doesn't settle down to a pattern you are happy with soon, I would seriously consider asking about unilateral injections. For some of us (not all) it resolves the loss of voice problem straight after Botox, and a relatively high dose (10 units in my case) ensures the benefit is still 4-6 months.

Good luck!

David Barton (AD/SD, Auckland, NZ)







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